Change in the number of presses/sequence for saline-treated animals. (Left) Number of presses/sequence across the 4 conditions (time: before/after and forelimb: contra/ipsilateral) for saline-treated animals. There was only small effect for time. Two-way repeated-measures ANOVA, time: F(1,5) = 7.704, p = 0.0391, forelimb: F(1,5) = 2.007, p = 0.2157, time x forelimb: F(1,5) = 0.01041, p = 0.9227. There was not any significant change in the number of presses/sequence after saline treatment, either contralaterally (3.40 ± 0.35 to 2.73 ± 0.33, multiple comparison test after two-way repeated-measures ANOVA, t(5) = 1.408, p = 0.3885) or ipsilaterally (3.06 ± 0.31 to 2.46 ± 0.45, multiple comparison test after two-way repeated-measures ANOVA, t(5) = 1.264, p = 0.4552). (Right) Ratio of presses/sequence after treatment, normalized to the one before treatment for both ipsilateral and contralateral forelimbs (normalization of data presented on the left panel). There was no significant difference between ipsilateral and contralateral change (paired t test, t(5) = 0.4441, p = 0.6755).