Illustration from Scientific Research

All cells, cytokines, and membrane proteins represented have been shown to be either reduced (Immune evasion; left side) or increased (Immune attack; right side) after mutant-specific KRAS inhibition in different models of colon, lung, and pancreatic cancer.*Although, Tregs and PD-L1 expression are considered immune evasive mechanisms, they increase within the tumor microenvironment upon KRAS inhibition. Created with BioRender.com.

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