Transmitter release constantly relies on P/Q-type Ca2+channels during development. Top: Average IPSCs in BC-PC pairs before and after application of 1 μM ω-agatoxin IVa (left), 1 μM ω-conotoxin GVIa (center), and 0.5 μM SNX-482 (right) for P14–16. Bottom: Plot of IPSC peak amplitude, normalized to control value, against experimental time during application of 1 μM ω-agatoxin IVa (red), 1 μM ω-conotoxin GVIa (blue), 0.5 μM SNX-482 (green), and mock application of control solution (black).
