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Timeline representation of vaccine administration, SARS-CoV-2 infection, and serum collection intervals for each cohort. The cohort that received a second BA.5 bivalent vaccine (BA.5 BV 2) was previously described. Indicated timepoints represent the median in days for each cohort, with day 0 defined as the day of the initial SARS-CoV-2 vaccination. Numbers of participants for each group receiving a fourth wild-type (WT) monovalent vaccine is indicated. n, sample size.

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