Bar Plot from Scientific Research

The effects of TTC1 depletion on ER morphology in RPE1 ZIM3 CRISPRi cells, assessed through immunostaining with Sec61beta and calculated as in (A). Error bars show mean +- SD of 9–10 images (9, A; 10, B), each containing 4–6 cells for an average of ~50 cells per condition. Statistical significance was evaluated using the Welch corrected unpaired t test.****p < 0.0001. ns (non-significant), p > 0.05. p-value for ER fragmentation: 0.9954.

DOI