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Normalized Hi-C contact maps (2 kb binning) showing cis interactions along the arm of chromosome 7, 80–160 kb from left telomere, in G2/M-arrested wild-type and top2-4 cells. Lines on top and to the left of the panels: green, cohesin binding sites in top2-4 mutant; blue, Smc5/6 binding sites in top2-4 mutant; light blue arrow: example of increased cis interactions between Smc5/6 binding sites in top2-4 cells.
#Heatmap#Hi-C Contact Maps#Cis Interactions#Chromosome 7#G2/M-arrested Cells#Wild-type Cells#top2-4 Cells#Cohesin Binding Sites#Smc5/6 Binding Sites
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