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ATAC-seq was performed with lipid-A-stimulated macrophages (0, 30, 60, and 120 min) in the absence and presence of CHX. Peaks induced >5-fold were separated into eight bins based on sensitivity of peak induction to CHX, with motif enrichment determined as in (A). Bins 1 and 8 contain peaks with the greatest (secondary response) and least (primary response) CHX sensitivity, respectively. Arbitrary separations between the primary and secondary responses are shown.
#Heatmap#ATAC-seq#Macrophages#Lipid-A Stimulation#CHX#Peak Induction#Motif Enrichment#Primary Response#Secondary Response
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