Percent of IGHV1-69/IGKV3-20 antibodies with the indicated amino acid length of heavy-chain CDR3, for antibodies that bind self-IgG (RF, red,n= 17) and antibodies that bind HCV E2 (E2, blue,n= 10). The black line denotes corresponding length distribution for 1,343 IGHV1-69 IgM antibodies of unknown specificity, representing the naive repertoire (<2% SHM) from PBMCs of 61 healthy donors. Points show mean ± SD.