Representative images of kidney histology stained with Masson trichrome blue and Picrosirius red, and quantification of interstitial collagen expression in the kidneys of WT and Tet2 -/- mice 28 days after injury (n = 6 mice each). Data were analyzed using a two-tailed Student’s t-test or two-way ANOVA followed by Tukey’s or Bonferroni’s post hoc tests and are presented as the mean ± s.e.m. * P < 0.05, ** P < 0.01, *** P < 0.001. Scale bar, 50 m.