Enrichment of tissue/stage-matched DHS (a) or H3K27ac peaks (d) in proximity to the other end of all significant interactions (schematic, top). Bottom, frequency of DHS within 500 bp of the other end in the respective condition, for all significant (filled circle) or nonsignificant (empty circle) interactions. DHS are more frequently at the other end of interactions at 10–12 h, compared to 6–8 h (a). Color shade (filled circles) indicates P value (two-sided Fishers exact test). Enrichments for E or P baits are shown separately.
