Violin plots/boxplots showing quantitative changes in DHS signal (b) or H3K27ac ChIP–seq signal (e). The direction of change in DHS signal correlates with direction of change in interaction frequency (b). The direction of H3K27ac change correlates with changes in interaction frequency, especially at 10–12 h (e). log 2 (FC) at other ends (<500 bp) of E/P Capture-C baits with decreased (turquoise), constant (yellow) or increased (brown) interactions across the same conditions (tissue or time). Boxplot, center = median; upper and lower bounds = interquartile range; whiskers = minimum and maximum.
