Heatmap from Scientific Research

Numbers of SNPs that were nominally significant (P < 1 x 10 -6) in the IPF GWAS meta-analysis and also eQTL (blue), the numbers of significant colocalizations between cell type and bulk eQTLs and three IPF GWAS, as well as childhood-onset and adult-onset asthma GWAS (red). Shown are the proportion of cells expressing the gene (orange) and the posterior probabilities for a single shared causal variant between the tested cell types and the GWAS for the selected top IPF-associated genes (MUC5B, DSP, KANSL1, KANSL1-AS1, shown in green) across 27 cell types with at least one colocalized gene.

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