Heatmap from Scientific Research

Significantly upregulated pathways induced by TGF-β treatment and restoration by INS018_055 (055) or shTNIK-1. Gene ontology (GO) enrichment (left, middle) and KEGG analysis (right). n = 3 in each condition. Enrichment analysis was performed using the gseapy.enrichr Python package. P values were computed using Fisher’s exact test (one-tailed hypergeometric test). Adjusted P values ( q values) were calculated using the Benjamini–Hochberg method for correction for multiple-hypothesis testing. ECM, extracellular matrix; NS, not significant.

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