Comparison of inferred intratumoral cell state proportions across tumor subtypes. T EX , terminal exhausted T cells; myCAF, myofibroblast-like cancer-associated fibroblasts. Box plots indicate the median (center lines), interquantile range (hinges) and 1.5 interquartile range (whiskers). n = 5,366 and 1,888 intratumoral spots for TNBC and MBC, respectively. Two-sided independent two-sample t -test was performed. P < 1 x 10 -30 , 1.20 x 10 -38 , 4.21 x 10 -220 , 8.06 x 10 -30 , 4.80 x 10 -68 and 3.26 x 10 -17 , sequentially.
