Boxplots of LFC in pegRNAs at D34 in Nutlin-treated condition separated by variant class for pegRNAs 10% editing and 20% editing. Statistics shown for two-sided t -test with Bonferroni correction. * P 0.05; ** P 0.01; *** P 0.001; **** P 0.0001; NS, not significant ( P > 0.05). g , Nonsense versus missense ( P = 0.02996), versus INS ( P = 0.05716), versus DEL ( P = 1.0), versus silent ( P = 0.0002895).
