Δ F/F of RCaMP3 and cAMPinG1-ST during and after the visual stimuli. n = 12 trials, n = 3 mice. Paired two-tailed t -test. Responded (during stim) versus non-responded (during stim): P = 1.5 × 10 −7 ; responded (during stim) versus responded (after stim): P = 2.1 × 10 −4 ; non-responded (during stim) versus non-responded (after stim): P = 5.1 × 10 −4 .