Δ F/F in response to APs (jRGECO1a, n = 152, 198, 124 and 44 events for 1, 2, 3 and 4 APs, respectively; RCaMP3, n = 228, 139, 159 and 17 events for 1, 2, 3 and 4 APs, respectively). Unpaired two-tailed t -test. P = 4.5 x 10 -58 (1AP); P = 1.8 x 10 -93 (2AP); P = 1.2 x 10 -60 (3AP); P = 3.8 x 10 -17 (4AP).
