Barplot showing the stoichiometry obtained from the DIP-MS experiments of UXT and PFDN2 for representative complexes in the PFD and PFDL interaction network as defined in Supplementary Table 5 . Stoichiometry was defined as the ratio between the protein having the lowest full-width at half-maximum peak area in a complex and all the other proteins in the same peak group. The dotted line highlights a stoichiometry of 1.00, which correspond to the literature-reported value for PFDN, PFDL as well as CCT/TRiC. Error bars indicate the standard deviation across six DIP-MS experiments (PFDN2, n = 3 biologically independent experiments; and UXT, n = 3 biologically independent experiments). Due to missing values, a few proteins have fewer replicates and/or points. Data are presented as mean values s.d.
