Line Plot from Scientific Research

DMS line plots for analyses of sera from mice that were immunized as shown in Figure 4A. DMS was conducted using a SARS-CoV-2 Beta RBD library. The x axis shows RBD residue positions, and the y axis shows the total sum of Ab escape for all mutations at a given site, with larger values indicating greater Ab escape. Each faint line represents a single antiserum with heavy lines indicating the average of n= 4 sera for each group. Lines are colored differently based on RBD epitopes from the 4 major classes (color definitions are shown in the legend below this panel and gray for residues not assigned to an epitope).

DOI