Illustration from Scientific Research

The schematic diagram showing the domain structures of TcsH and TMPRSS2, as well as the domain boundaries for TcsH 2236-2618 and TMPRSS2 ECD used for cryo-EM studies. GTD glucosyltransferase domain, CPD cysteine protease domain, DRBD delivery and receptor-binding domain, CROPs combined repetitive oligopeptides domain. The CROP unit-I to VI were marked in the enlarged CROPs domain; blue and pink bars represent SRs (short repeats) and LRs (long repeats) respectively. TM transmembrane domain, LDLRA low-density lipoprotein receptor class A domain, SRCR scavenger receptor cysteine-rich domain, SPD serine protease domain.

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