Sera neutralizing activity against: SARS-CoV-2 WH-1 variants after viral challenge. Neutralization data were analyzed as indicated in b . S-2P group: n =6 on day 3, n =6 on day 6, n =8 on day 14, n =1 on clinical endpoints. S-V987H group: n =6 on day 3, n =6 on day 6, n =9 on day 14. Unvaccinated-challenged (Infected control) mice: n =6 on day 3, n =2 on day 6, n =8 on clinical endpoints. Uninfected and unvaccinated mice (Uninfected control): n =10 on day 14.
