Erythroid production site frequency (top, n = 3 bones each from 3 mice) and number of CFU-Es per site ( n = 10 randomly selected production sites from 3 bones each from 3 mice) in control (ctl) or 2 days after phlebotomy (Phl). Statistical differences were calculated using two-tailed unpaired Student’s t -tests if the data were normally distributed or two-tailed Mann–Whitney test if they were not normally distributed.