Heatmap from Scientific Research

A heat map showing the percentage of PNPs in each class that have >85% similarity to a bioactivity cluster profile and induction values >15%. The PNPs were measured at various concentrations (≤50 µM), generating several profiles for each PNP. For each PNP, the profile with the highest similarity to a bioactivity cluster was selected for this analysis. L/CH, lysosomotropism/cholesterol homeostasis. For heat maps of bioactivity cluster similarities of individual profiles of hit compounds, see Supplementary Figs. 15 and 16.

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