Uridine rescue assay. HCT116 cells were treated with either DMSO (control), E13 or E13 in the presence of uridine (100 µM). Cell confluence was used as a measure of cell proliferation and was monitored over a 96 h period using an IncuCyte ZOOM/S3. Data are mean values ± s.d. of four independent replicates ( n = 4).