Schematics of the orthogonal IDR-core systems; the residue charge distributions of FUS N and DDX4 N are quantified using the net charge per residue (NCPR). The 24-mer FTH1 and the 60-mer I3-01 K129A cores are used for studying the interactions between condensate phases formed by different IDRs, for example, FUS N and DDX4 N .
