Four different dynamics exemplified by different microbial SGBs with different dynamics in patients with PFS >=12 (n0 = 62, n1 = 77, n2 = 38 and n3 = 30) and PFS <12 (n0 = 74, n1 = 69, n2 = 34 and n3 = 24) months, where the slope of the patients with PFS >=12 months is relatively unchanged across the study visits compared to the slope of the patients with PFS <12 months (dynamics 2c, Extended Data Fig. 7c). The y axis shows the expected abundance (represented in centered log ratio coordinates) for each study visit (x axis). The corresponding inset figures show the average difference between patients with PFS >=12 and PFS <12 months at each study visit, including its 90% credible interval. The number (n) represents the number of patient samples at each visit for patients with PFS >=12 and PFS <12 months.