Heatmap from Scientific Research

On each plot, one donor’s individual SPNs are ordered from left to right by the length of their HTTCAG repeat (the columns of the heatmap). Each row shows expression data for a specific gene in these SPNs. (The genes shown are genes found to change in expression with repeat expansion.) Shades of each facet show the level of expression of that gene in that SPN, relative to the average SPN with repeat length <150 in that donor. Example trajectories for individual genes are in Figure S6A.

DOI