Scatter Plot from Scientific Research

Comparisons (volcano plots) of gene expression between sets of SPNs, sampled from the same person with HD but with CAG-repeat lengths in different ranges. p values (y axis) are derived from a Wilcoxon test across the individual SPNs in each group. Fold changes (x axis) are the log2 ratio of the group averages (positive fold change indicates higher expression in the SPNs with longer repeats). Analyses for all six donors are in Figures S4B–S4E.

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