Schematic representation of U1 snRNA primary sequence (annotated as RNU1-1 in RefSeq ) with the associated University of California Santa Cruz (UCSC) Genome Browser tracks for mammalian conservation ( PhastCons ). The tiling antisense DNA oligonucleotides used for depletion of U1 snRNA in TREX (three in total) are depicted on the tracks. Scale, 100 bases. chr, chromosome.