Heatmap showing relative expression levels of DEGs in mLECs involved in mitochondrial metabolism. n = 3 mice in each group in data c - g . Data in b , c , f are presented as mean SEM, and analyzed by one-way ANOVA with Sidaks multiple comparison test for comparisons of multiple groups ( b ), or two-tailed unpaired Students t-test for two-group comparisons ( c , f ). P values in d was calculated with clusterProfiler using the empirical phenotype-based permutation test, without any adjustments for multiple comparisons. The statistical tests involved two-sided analysis. Source data are provided as a Source data file.