Retinal cryosections from 2-week-old B6, Rho P23H , and Rho G188R mice were colabeled with PROTEOSTAT (red) and an anti-ubiquitin antibody (green). Nuclei were labeled with NucBlue (blue). Lower magnification images (scale bar, 50 m) are shown on top and higher magnification maximum intensity projection images (scale bar, 5 m) in regions highlighted by white boxes in the lower magnification images are shown on the bottom. Separated individual images showing only a single label are presented in Supplementary Fig. 4 .