CR rates in the intention-to-treat population. The tumor response was assessed using a validated computer algorithm in accordance with the International Myeloma Working Group response criteria 26 . Complete response (CR) or stringent CR (sCR) was achieved at any time during the trial. The MantelHaenszel estimate of the common odds ratio for stratified tables was used. The stratification factors were ISS disease stage (I, II or III) and age/transplant eligibility (<70 years and transplant ineligible, <70 years and transplant deferred or >=70 years). An odds ratio >1 indicates an advantage for D-VRd. The P value (two sided) was calculated using the CochranMantelHaenszel 2 test. PR, partial response; VGPR, very good partial response.
