Comparison of TNF co-production by INF + cells after brief ex vivo stimulation with gp33 or np396 peptide. Spleen cells were isolated on day 4.5 after infection with LCMV Armstrong and pre-gated as KLRG1 - TCF1 + TOX + (TOX + ) or KLRG1 - TCF1 + TOX - (TOX - ) T cells. n = 4; * P = 0.0417, ** P = 0.0046 (two-tailed paired t -tests). Data are representative of three ( a ) or two ( b , f ) independent experiments or derived from a single experiment ( c e ).
