Ratio of AT2 versus AT1 cell counts across samples compared between the present spatial dataset and a recent scRNA-seq dataset 9 . Outlier samples are shown as individual points. Samples without counts for both AT1 and AT2 cells were not included in the analysis. Mean ratios across all samples are listed above. Boxplots show the median, with box hinges extending to the first and third quartiles and the whiskers extending to the largest (upper whisker) or smallest (lower whisker) value with a maximum of 1.5 IQR above and below. Sample sizes—spatial control, n =10; disease, n =34; ref. 9 control, n = 16 and disease, n = 22.