cART=combination antiretroviral therapy. IPTp=intermittent preventive treatment in pregnancy. ITT=intention to treat. Full eligibility criteria could not be assessed in these women, who either expressed hesitation in joining the study or whose partner, spouse, or another family member discouraged them from joining the research study. Study drug refers to receipt of at least one course of intermittent preventive treatment with dihydroartemisininpiperaquine or placebo. Three participants (co-trimoxazole plus dihydroartemisininpiperaquine, n=2; co-trimoxazole plus placebo, n=1) did not receive study drug because they had malaria at enrolment and were treated with artemetherlumefantrine and were lost to followup before their first course of study drug scheduled 1 month later. The participant was randomly assigned to co-trimoxazole plus dihydroartemisininpiperaquine but later found to meet the exclusion criteria (twin pregnancy). Because the participant received the study drug, she is included in the safety population but not in the modified ITT population or per-protocol population.
02631-4%2Ffig1_a.webp&w=1920&q=75 "Learn How to Make Flowchart for Your Research Paper")