CRISPR dropout screen by tilling the sgRNAs targeting the RBM5 exons in OCIAML2 cells at day 7. The known protein domains (including RRM1, RRM2, ZF-RanBP, ZF-C2H2, OCRE, and G-patch) were highlighted in purple boxes, while the predicted essential domains were highlighted in brown boxes. The Z-score was calculated based on the average count of all sgRNAs targeting a 10-kb window in the genome.
