Bar Plot from Scientific Research

Competition-based proliferation assays comparing the impact of sgRNAs on MOLM13, THP1, and OCIAML2 cell fitness, in the context of co-transduction with Venus empty vector control, RBM5-wild-type cDNA (WT), RBM5-sgRNA1-resistant mutant cDNA (PAM-MUT) (all monitored by Venus reporter). Data shown are means ± SEM from three independent experiments. * P < 0.05, ** P < 0.01, *** P < 0.001, unpaired Student’s t -test

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