Plot of cumulative distribution function for p -value of energy test of gene sets. ClinGen-HI&TS genes: haploinsufficient/triplosensitive gene from ClinGen. pHaplo-HI: haploinsufficient genes according pHaplo score. pTriplo-TS: triplosensitive genes according pTriplo score. SaPS top-score: genes with top 5% SaPS scores.