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VEGFC was injected through the AC, IVT or ICM administration route. Two days later, dye was IVT injected into the eye, and the percentage of dye retention was measured 12 h after dye injection (control, n = 12; AC, n = 19; IVT, n = 20; CSF (2 g), n = 20; CSF (6 g), n = 10) **** P < 0.0001; *** P < 0.0002. Data are shown as mean s.e.m. P values were calculated using a one-way ANOVA with multiple comparisons testing (Dunnett) or two-tailed unpaired Student’s t -test.

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