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Quantification of TDP-43HA-transgenic cells in e. Each data point represents a sum of all TDP-43HA + cells counted from 182 fields of view of an independent well and normalized with DAPI, shown as a percentage of the of 1-week condition. Between 189 and 16,453 cells were analysed per data point. Two-way ANOVA (mixed model) followed by Tukeys multiple comparisons test (mean of each dataset compared with the mean of every other dataset). Different shades of grey indicate independent experiments. Data shown are mean s.d. TDP-43HA only versus TDP-43HA + NPTX2 shRNA, P = 0.0337; TDP-43HA + control shRNA versus TDP-43HA + NPTX2 shRNA, P = 0.0312.
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