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Mice that received i.t. adoptive transfer of 106 murine bone marrow-derived PMNs pretreated with Yoda1 showed marked improvement of Pseudomonas aeruginosa clearance at 16 h post-i.t. instillation of 106 colony-forming unit (CFU) bacteria per mouse, as compared with vehicle control. Data were obtained from 5 to 6 mice per group from 3 independent experiments. Additional information is provided asFigures S2C–S2J andS3A–S3E.
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