Heatmap from Scientific Research

Heatmap of concordance between this study and previous studies of trained immunity. Regions with differential chromatin accessibility between trained immunity non-responders and responders (top) and upon BCG vaccination among the responders (center and bottom) were compared with literature-curated genomic regions with increased chromatin accessibility or corresponding histone marks in trained immunity (left) and with literature-curated genes with decreased gene expression in trained immunity (right).

DOI