Protein Structure from Scientific Research

Open access visualization of Protein Structure, Structural Data, IFT-A, Cilium, STA Map
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DOI: 10.1016/j.cell.2024.01.005

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Integration of diverse structural data to produce a model of IFT-A within the cilium. From left to right: STA map generatedin situas in (A), high-resolution map of an isolated IFT-A complex generated by single-particle analysis (SPA),188AlphaFold2 (AF2) structure prediction of IFT-A proteins, distance restraints (pink) between IFT-A proteins derived from cross-linking mass spectrometry (XL/MS) of intact cilia and enriched fractions,152and the final integrated model of the IFT-A complex.

#Protein Structure#Structural Data#IFT-A#Cilium#STA Map#Single-Particle Analysis#AlphaFold2#Cross-Linking Mass Spectrometry

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