Quantification of data shown in ( c ) and ( d ). Over 60 cells were obtained from 57 imaging views ( e , DMSO, n = 5; D-2-HG, n = 5, D-2-HG + alphaKG, n = 6, D-2-HG + TET1, n = 8, D-2-HG + TET2, n = 7). * p < 0.05, ** p < 0.01. e All indicated p < 0.0001; f DMSO vs D-2-HG, p < 0.0001; D-2-HG vs D-2-HG + alphaKG, p < 0.0001; D-2-HG vs D-2-HG + TET1, p = 0.0069; D-2-HG vs D-2-HG + TET2, p = 0.0277; group differences were tested with one-way ANOVA. Data are mean SEM from three independent experiments.
