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ChIP-qPCR shows the recruitment of BRCA2, RAD51, and H2A.X modification around the Sce-I site. DD-Sce-I-GR DRGFP U2OS cells were treated with 0.5 M Shield1 and 0.2 mM TA in the presence of 0.5 mM D-2-HG with 10 mM KG. ACTB loci were used as the negative control. Data are presented as mean values SEM from three independent experiments. Source Data are provided as a Source Data file.

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