Quantification of the cells with RAD51 recruitment to DSB sites. A total of 40 cells from 5-9 views (DMSO, n = 7; D-2-HG, n = 8, D-2-HG + KG, n = 5, D-2-HG + TET1, n = 6, D-2-HG + TET2, n = 7) were obtained for quantifications. ** p < 0.01. c D-2-HG vs D-2-HG + KG, p < 0.0001; D-2-HG vs D-2-HG + TET1, p = 0.0006; D-2-HG vs D-2-HG + TET2, p < 0.0001; Group differences were tested with one-way ANOVA. Data are mean SEM from three independent experiments.