Cartoon representation of each mechanism of tetracycline resistance. (Not drawn to scale.) TET tetracycline, DOX doxycycline, CTC chlortetracycline, DOX doxycycline, MIN minocycline, MET metacycline, TIG tigecycline, OMA omadacycline, ERA eravacycline, EFF efflux pump, RPP ribosomal protection protein, DES1 type 1 tetracycline destructase, DES2 type 2 tetracycline destructase.