Microscopy from Scientific Research

Summary schematic. Retrieving a learned (drug-cue-place) association involves transient coordination of multiple short-lived beta-paced network activities that are co-enhanced in recall, decrease in extinction, and re-occur in renewal. This brain-distributed pattern is actuated by 4-Hz-paced VTA glutamatergic cells forming a one-to-many-region pathway. This cross-network coordination could yield a cohesive (meta-) ensemble of neurons serving robust memory expression.

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