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VTA VGlut2; DAT neuron suppression reduced downstream beta amplitude and prevented renewal of cocaine-biased behavior. Intersectional strategy for VTA glutamatergic/dopaminergic neuron targeting in double-transgenic VGlut2-Cre; DAT-Flp mice injected with a Cre- and Flp-dependent ArchT-eYFP construct (top), used with quintuple-brain-region recordings and phase-informed bilateral VTA light delivery (bottom).
#Workflow#Flowchart#Illustration#VTA#VGlut2#DAT Neuron#Beta Amplitude#Cocaine-Biased Behavior#Glutamatergic Neurons#Dopaminergic Neurons#VGlut2-Cre Mice#DAT-Flp Mice#ArchT-eYFP
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