MM047, A375 cells were treated with BET (ARV-771 100 nM for MM047, 25 nM for A375), BRAF, and MEK inhibitors (dabrafenib 2.5 nM, trametinib 0.5 nM, for A375, trametinib only 20 nM for MM047), siTCF4, si CTRL, or a combination thereof. The heatmap summarizes all data collected at the last time point (150 h).
